KATLab

An up-to-date list can be found on pubmed

Artemisinin susceptibility in the malaria parasite Plasmodium falciparum: propellers, adaptor proteins and the need for cellular healing. Sutherland CJ, Henrici RC, Artavanis-Tsakonas K. FEMS Microbiol Rev. 2021 May 5;45(3):fuaa056. doi: 10.1093/femsre/fuaa056. PMID: 33095255

Ubiquitin-Like Modifiers: Emerging Regulators of Protozoan Parasites. Karpiyevich M, Artavanis-Tsakonas K. Biomolecules. 2020 Oct 3;10(10):1403. doi: 10.3390/biom10101403. PMID: 33022940; PMCID: PMC7600729.

CD82 controls CpG-dependent TLR9 signaling. Khan NS, Lukason DP, Feliu M, Ward RA, Lord AK, Reedy JL, Ramirez-Ortiz ZG, Tam JM, Kasperkovitz PV, Negoro PE, Vyas TD, Xu S, Brinkmann MM, Acharaya M, Artavanis-Tsakonas K, Frickel EM, Becker CE, Dagher Z, Kim YM, Latz E, Ploegh HL, Mansour MK, Miranti CK, Levitz SM, Vyas JM. FASEB J. 2019 Nov;33(11):12500-12514. doi: 10.1096/fj.201901547R. Epub 2019 Aug 13. PMID: 31408613; PMCID: PMC6988855.

Nedd8 hydrolysis by UCH proteases in Plasmodium parasites. Karpiyevich M, Adjalley S, Mol M, Ascher DB, Mason B, van der Heden van Noort GJ, Laman H, Ovaa H, Lee MCS, Artavanis-Tsakonas K. PLoS Pathog. 2019 Oct 28;15(10):e1008086. doi: 10.1371/journal.ppat.1008086. PMID: 31658303; PMCID: PMC6837540.

Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis. White RR, Ponsford AH, Weekes MP, Rodrigues RB, Ascher DB, Mol M, Selkirk ME, Gygi SP, Sanderson CM, Artavanis-Tsakonas K. PLoS Pathog. 2016 Nov 21;12(11):e1005977. doi: 10.1371/journal.ppat.1005977. eCollection 2016 Nov. PMID: 27870901

Stabilization of an unusual salt bridge in ubiquitin by the extra C-terminal domain of the proteasome-associated deubiquitinase UCH37 as a mechanism of its exo specificity.
Morrow ME, Kim MI, Ronau JA, Sheedlo MJ, White RR, Chaney J, Paul LN, Lill MA, Artavanis-Tsakonas K, Das C.
Biochemistry. 2013 Apr 25.

How helminths use excretory secretory fractions to modulate dendritic cells.
White RR, Artavanis-Tsakonas K.
Virulence. 2012 Nov 15;3(7).

Characterisation of the Trichinella spiralis deubiquitinating enzyme, TsUCH37, an evolutionarily conserved proteasome interaction partner.
White RR, Miyata S, Papa E, Spooner E, Gounaris K, Selkirk ME, Artavanis-Tsakonas K.
PLoS Negl Trop Dis. 2011 Oct;5(10):e1340.

The tetraspanin CD82 is specifically recruited to fungal and bacterial phagosomes prior to acidification.
Artavanis-Tsakonas K, Kasperkovitz PV, Papa E, Cardenas ML, Khan NS, Van der Veen AG, Ploegh HL, Vyas JM.
Infect Immun. 2011 Mar;79(3):1098-106.

Structural studies and characterization of the Plasmodium falciparum ubiquitin and Nedd8 hydrolase UCHL3.
Artavanis-Tsakonas K, Weihofen WA, Antos JM, Coleman BI, Comeaux CA, Duraisingh MT, Gaudet R, Ploegh HL.
J Biol Chem. 2010, Feb 26;285(9):6857-66.

Substrate filtering by the active site crossover loop in UCHL3 revealed by sortagging and gain-of-function mutations.
Popp MW, Artavanis-Tsakonas K, Ploegh HL.
J Biol Chem. 2009, Feb 6;284(6):3593-602.

Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activity.
Walters BJ, Campbell SL, Chen PC, Taylor AP, Schroeder DG, Dobrunz LE, Artavanis-Tsakonas K, Ploegh HL, Wilson JA, Cox GA, Wilson SM.
Mol Cell Neurosci. 2008 Dec;39(4): 539-48.

Tubulation of Class II MHC compartments is microtubule-dependent and involves multiple endolysosomal membrane proteins in primary dendritic cells.
Vyas JM, Kim Y, Artavanis-Tsakonas K, van der Veen A., Love JC, Ploegh HL.
J Immunol. 2007, 178(11):7199-210.

Apicomplexan UCH-L3 retains dual specificity for ubiquitin and Nedd8 throughout evolution.
Frickel EM, Quesada V, Muething L, Gubbels MJ, Spooner E, Ploegh H, Artavanis-Tsakonas K.
Cell Microbiol. 2007, 9(6):1601-10.

Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification.
Artavanis-Tsakonas K, Love JC, Ploegh HL and Vyas JM.
Proc Natl Acad Sci. 2006, 103(43):15945-50.

Identification by functional proteomics of a deubiquitinating/deNeddylating enzyme in Plasmodium falciparum.
Artavanis-Tsakonas K, Misaghi S, Comeaux CA, Catic A, Spooner E, Duraisingh MT, Ploegh HL.
Mol Microbiol. 2006, 61(5):1187-95.

Uninfected erythrocytes inhibit P. falciparum-induced cellular immune responses in whole blood assays.
Struik SS, Omer FM, Artavanis-Tsakonas K and Riley EM.
Blood. 2004, 103(8):3084-92.

Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.
Artavanis-Tsakonas K, Eleme K, Davis DM and Riley EM.
J Immunol. 2003, 171(10):5396-405.

The war between the malaria parasite and the immune system: immunity, immunoregulation and immunopathology.
Artavanis-Tsakonas K, Tongren JE and Riley EM.
Clin Exp Immunol, 2003, 133(2):145-52.

Innate immune responses to Plasmodium falciparum malaria: early IFN-γ production is derived from NK cells and is preferentially induced by live rather than dead parasites.
Artavanis-Tsakonas K and Riley EM.
J Immunol, 2002, 169: 2956-2963.